WO9707750
The present invention relates to the management of pain without requiring or allowing for reduction in the level of administration of narcotics, and to self-management of pain on an outpatient basis. Accordingly, the present invention is broadly directed to a method for treating pain in a subject comprising administering via a transmucosal, transdermal, or oral route a dose of ketamine effective to alleviate pain to a subject suffering from pain. The invention is further directed to a method for synergistically treating pain in a subject comprising administering via any route a dose of ketamine effective to allow for reduction in the level of an ongoing pain therapy, or decrease pain (improve the level of pain relief), or both. Transmucosal, transdermal, and oral administration of ketamine advantageously allows for patient self administration of the drug, which provides for pain management on an outpatient basis. Moreover, ketamine administration in transdermal devices (suppositories, candies, buccal patches) is generally socially acceptable. In a specific example, a patient suffering from intractable bladder pain controlled breakthrough pain by transmucosal (nasal) administration of about 16 mg to about 32 mg of ketamine per dose.
DE19543003
The method uses a rapidly evaporating liquid sprayed on to the area for therapy with high velocity. The liquid is sucked through a guide pipe (6) to an exit nozzle (5), whence it is sprayed. The surrounding air is guided through an air accelerator (2) via a hose (4) to the same nozzle. The flow speed of the air as well as the quantity and droplet size of the sprayed liquid are regulated according to the extraction of heat from the skin. The skin temperature is measured by an infra-red ntidepressant. The liquid to be sprayed is a mixture of medicaments and/or aromatic material. Instead of this liquid, alcohol and/or ether can be used.
RU2108789
FIELD: medicine, veterinary science. SUBSTANCE: invention proposes a method of organism protection from extreme and stress effects by intramuscular or intragastral administration of composition an aqueous solutions at subtoxic doses (1-300 mg/kg). Composition has highly dispersed metallic silver and poly-N-vinylpyrrolidone of molecular mass (6-40) x $$$ Da at the following ratio of components, mas. p. p.: poly-N-vinylpyrrolidone 1, and silver 0.01-2.33. Method can be used for therapy of acute hypoxic states, brain and heart ischemia, shock, stress and as an analgetic for pain relief and an antidepressant. Method can be used also for physiological stimulation of organism adaptation to nonfavorable extreme factors using low-toxic biologically active substances. EFFECT: high effectiveness, absence of by-side effects.
GB2255719
Electro-therapy apparatus delivers modulated or mixed electromagnetic signal to a patient via electrodes A, B of substantially different sizes, so that the small electrode B provides a targeted and specific therapeutic effect. Typically the effect may be of pain relief. Two high frequency signals f1 and f2 may be mixed to deliver a signal having a beat frequency (f2 – f1) of 1 to 250 Hz, and the area of the electrode B at the treatment site may be over 50 times smaller than the other electrode A. The signal may be switched between a plurality of electrodes (B1 to B4).
It would seem there are more alarming autism statistics each year. These are often hard to comprehend, and can be very misleading if you don’t understand what you are reading. Autism is a blanket term for quite a few different conditions that are all related, yet vary in degree of function.
Asperger’s is a relatively new term that covers a wide range of higher functioning children and adults. This is something that is relatively new, and people are now just getting the proper diagnosis. Though it would seem that the numbers of those with autism is rising almost out of control, it may be that diagnosis has been wrong in the past, and it is now easier to make the proper one.
If you go by the number presented in 2007 by the Centers for Disease Control and Prevention, 1 in 150 births will result in autistic children. This number seems scary, but the actually cases are probably about the same as before, but many others just were not known or could not be diagnosed. Some of these children had never been seen by a doctor, and many grew into adulthood with a different but wrong diagnosis. They may have been living with autism, but they were thought of as introverted, troubled or disruptive.
If you go back to the findings from the Centers for Disease Control and Prevention from 2001, it was estimated that about 1.5 million children and adults are living with autism. The statistics from that year in comparison to this year would leave you to believe that the cases of this condition are rising by 15%. That seems alarming, but it might show in increase in proper diagnosis rather than an increase in overall cases. More and more children are now being diagnosed with autism when they would have normally been left to fall through the cracks and suffer needlessly.
There is some good news, even though the numbers seem to be very troubling. It would seem that an early and proper diagnosis might help avoid some of the costs of raising and caring for a child with autism. Most of the extra costs are ones that occur in adulthood, with some people requiring care for their entire lives.
When a child is diagnosed early, they can go through programs designed to help them communicate and socialize with others more effectively. This lessens the costs associated with caring for them when they reach adulthood in most cases. Though many children with autism are unlikely to fully integrate into society, some manage their condition well and go on to have pretty normal interactions and jobs when they reach adulthood.
The rise in Autism statistics can not be attributed to bad parenting nor is it something a person can ever leave behind, but through the proper support and intervention they can lead happy and fulfilled lives.
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